Giovanni Barillari Selected Research

HIV Protease Inhibitors

12/2020	HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
5/2018	The Impact of Human Papilloma Viruses, Matrix Metallo-Proteinases and HIV Protease Inhibitors on the Onset and Progression of Uterine Cervix Epithelial Tumors: A Review of Preclinical and Clinical Studies.
5/2017	Inhibition of MMP-9 expression by ritonavir or saquinavir is associated with inactivation of the AKT/Fra-1 pathway in cervical intraepithelial neoplasia cells.
10/2014	The HIV protease inhibitor indinavir down-regulates the expression of the pro-angiogenic MT1-MMP by human endothelial cells.
1/2011	Human immunodeficiency virus protease inhibitors reduce the growth of human tumors via a proteasome-independent block of angiogenesis and matrix metalloproteinases.
9/2003	Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth.
8/2003	HIV protease inhibitors as new treatment options for Kaposi's sarcoma.
2/2003	[HIV protease inhibitors for the treatment of Kaposi's sarcoma].
11/2002	Treatment of Kaposi's sarcoma--an update.
3/2002	HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma.

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Giovanni Barillari Research Topics

Disease

20	Neoplasms (Cancer) 12/2021 - 11/2002
9	Hemorrhage 01/2021 - 05/2006
9	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2011 - 03/2002
7	Acquired Immunodeficiency Syndrome (AIDS) 01/2011 - 04/2002
6	Venous Thromboembolism 10/2020 - 10/2010
5	Venous Thrombosis (Deep-Vein Thrombosis) 10/2020 - 01/2015
4	Hemophilia A (Haemophilia) 02/2021 - 08/2011
4	Carcinoma (Carcinomatosis) 12/2020 - 05/2012
4	Disease Progression 05/2018 - 07/2010
4	Pulmonary Embolism 01/2018 - 10/2010
3	Thrombosis (Thrombus) 01/2021 - 02/2014
3	Uterine Cervical Dysplasia 12/2020 - 05/2012
2	Adenocarcinoma 01/2021 - 01/2011
2	HIV Infections (HIV Infection) 12/2020 - 05/2012
2	Thrombocytopenia (Thrombopenia) 11/2020 - 02/2014
2	Atrial Fibrillation 10/2020 - 01/2017
2	Stroke (Strokes) 10/2020 - 01/2017
2	Neoplasm Metastasis (Metastasis) 06/2020 - 09/2003
2	Infections 08/2011 - 11/2002
2	Pre-Eclampsia (Preeclampsia) 03/2011 - 01/2003
1	Malignant Mesothelioma 01/2022
1	Carcinogenesis 12/2021
1	Persistent Infection 12/2021
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021
1	Liver Diseases (Liver Disease) 09/2018
1	Joint Diseases (Joint Disease) 09/2018
1	Body Weight (Weight, Body) 03/2017
1	Stomach Neoplasms (Stomach Cancer) 03/2017
1	Pruritus (Itching) 01/2017
1	Vomiting 01/2017
1	Nausea 01/2017
1	Huntington Disease (Huntington's Disease) 01/2015
1	Shoulder Fractures 08/2014
1	Fibrosis (Cirrhosis) 02/2014
1	Low Back Pain (Lumbago) 02/2013
1	Anemia 02/2013
1	Hypertension (High Blood Pressure) 02/2013
1	Respiratory Insufficiency (Respiratory Failure) 02/2013
1	Hemophilia B (Haemophilia B) 01/2012
1	Craniocerebral Trauma (Head Injury) 01/2012
1	Endoleak 08/2011

Drug/Important Bio-Agent (IBA)

10	HIV Protease InhibitorsIBA 12/2020 - 03/2002
9	AnticoagulantsIBA 01/2021 - 10/2010
6	Matrix Metalloproteinases (MMPs)IBA 12/2020 - 01/2011
6	Saquinavir (Invirase)FDA Link 12/2020 - 08/2003
5	CytokinesIBA 12/2021 - 11/2002
5	Indinavir (Crixivan)FDA Link 12/2020 - 08/2003
5	Proteins (Proteins, Gene)FDA Link 05/2018 - 03/2009
4	Ritonavir (Norvir)FDA Link 12/2020 - 09/2003
3	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 11/2020 - 03/2017
3	EnzymesIBA 06/2020 - 02/2003
3	tat Gene Products (tat Protein)IBA 10/2016 - 04/2002
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2011 - 06/2010
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2020 - 01/2015
2	Pharmaceutical PreparationsIBA 09/2018 - 02/2003
2	Vitamin K FDA Link 01/2018 - 02/2014
2	Trans-Activators (Trans-Acting Factor)IBA 10/2016 - 04/2006
2	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 08/2011 - 11/2002
2	Blood Coagulation Factors (Coagulation Factor)IBA 08/2011 - 05/2006
2	Protease Inhibitors (Protease Inhibitor)IBA 01/2011 - 09/2003
2	Telomerase (Telomerase Reverse Transcriptase)IBA 11/2010 - 07/2010
2	RNA (Ribonucleic Acid)IBA 11/2010 - 04/2010
2	Fibrinogen (Factor I)FDA Link 06/2009 - 05/2006
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Oncogene Proteins (Oncogene Protein)IBA 12/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2021
1	ABO Blood-Group SystemIBA 02/2021
1	von Willebrand FactorIBA 02/2021
1	Factor VIII (Coagulation Factor VIII)IBA 02/2021
1	Bortezomib (Velcade)FDA Link 01/2021
1	Tissue Inhibitor of Metalloproteinase-3IBA 12/2020
1	Lopinavir FDA Link 12/2020
1	Estrogens (Estrogen)FDA Link 12/2020
1	Factor Xa InhibitorsIBA 10/2020
1	Angiogenesis InhibitorsIBA 01/2020
1	Peptide Hydrolases (Proteases)FDA Link 05/2018
1	RivaroxabanIBA 03/2018
1	fibrin fragment D (D-dimer)IBA 06/2017
1	Dabigatran FDA Link 01/2017
1	Nerve Growth Factors (Neurotrophins)IBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 01/2015
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 10/2014
1	antineoplaston A10 (A 10)IBA 01/2012
1	Factor X (Stuart Factor)IBA 08/2011

Therapy/Procedure

15	Therapeutics 01/2021 - 11/2002
2	Radiotherapy 12/2021 - 01/2020
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2020
2	Highly Active Antiretroviral Therapy (HAART) 05/2012 - 09/2003
1	Transplantation 06/2020
1	Deprescriptions 09/2018
1	Polypharmacy 09/2018
1	Operative Surgical Procedures 08/2014
1	Hemiarthroplasty 08/2014
1	Duration of Therapy 10/2013
1	Blood Transfusion (Blood Transfusions) 02/2013
1	Laparotomy 02/2013
1	Cesarean Section (Caesarean Section) 02/2013
1	Vena Cava Filters (Inferior Vena Cava Filter) 02/2013
1	Thrombectomy 02/2013